Repare Therapeutics: Synthetic Lethality-Based Approach to Oncology Therapeutics


 

Pharmaceutical animation describing Repare Therapeutics' discovery and clinical pipeline for cancer therapy treatment. Their approach leverages synthetic lethality, where cancer cells have a genetic mutation that results in cell death when combined with a therapeutic drug that simultaneously alters another gene.

Client: Repare Therapeutics
Agency: Digizyme, Inc.
Contribution: Worked with team members and led storyboarding and animation
Year: 2023
Media: Autodesk Maya, Adobe Illustrator, Adobe After Effects


This animation describes Repare Therapeutics’ unique platform and pipeline for cancer therapy that leverages synthetic lethality. In this situation, the cancer cells have an alteration in a gene that by itself is survivable, but simultaneous alteration of another gene, such as through genetic modification or therapeutic drugs, results in cell death. Healthy cells, which lack the initial alteration, should remain healthy.